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M-PEG6-Hydrazide

CAT: 0013-GTR19225408-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19225408-01Size:100 mg
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Description
M-PEG6-Hydrazide is a polyethylene glycol (PEG) linker used in constructing PROTAC molecules for targeted protein degradation. It connects a target-binding ligand to an E3 ligase recruiter, facilitating the study of protein function in both cellular and in vivo research models via the ubiquitin-proteasome system.
CAS Number
1449390-64-0
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NN) CCOCCOCCOCCOCCOCCOC
Molecular Formula
C14H30N2O7
Molecular Weight
338.4
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

m-PEG6-Hydrazide
CAS Number1449390-64-0
PubChem CID118988092
IUPAC Name3-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanehydrazide
Molecular FormulaC14H30N2O7
Molecular Weight338.40
XLogP-2.2
Topological Polar Surface Area111
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count18
Heavy Atom Count23
Formal Charge0
Complexity257
SMILES
COCCOCCOCCOCCOCCOCCC(=O)NN
InChI
InChI=1S/C14H30N2O7/c1-18-4-5-20-8-9-22-12-13-23-11-10-21-7-6-19-3-2-14(17)16-15/h2-13,15H2,1H3,(H,16,17)
InChIKey
RCYPACRVXCTNNY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of m-PEG6-Hydrazide
CAS: 1449390-64-0
CID: 118988092
Formula: C14H30N2O7
MW: 338.40
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight338.40
XLogP3-2.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count18
Exact Mass338.20530130
Monoisotopic Mass338.20530130
Topological Polar Surface Area111 Ų
Heavy Atom Count23
Formal Charge0
Complexity257
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes