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Mal-VC-PAB-DM1

CAT: 0013-GTR19225327-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19225327-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mal-VC-PAB-DM1 is a cleavable drug-linker conjugate for constructing antibody-drug conjugates (ADCs) . It incorporates the cytotoxic maytansinoid DM1, which disrupts microtubule dynamics, enabling targeted delivery and potent antitumor activity in both in vitro and in vivo cancer research models.
CAS Number
1464051-44-2
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@@]12C[C@@] (O) (NC (=O) O1) [C@] ([H]) (OC) \C=C/C=C (C) \Cc1cc (OC) c (Cl) c (c1) N (C) C (=O) C[C@] ([H]) (OC (=O) [C@H] (C) N (C) C (=O) OCc1ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCCCCN3C (=O) C=CC3=O) C (C) C) cc1) [C@]1 (C) O[C@H]1[C@@H]2C
Molecular Formula
C61H82ClN9O17
Molecular Weight
1248.82
Storage Conditions
-20°C
Notes
For research use only.

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