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MC-Val-Cit-PAB-Auristatin E

CAT: 0013-GTR19225314Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19225314Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MC-Val-Cit-PAB-Auristatin E is a cleavable linker-payload for constructing antibody-drug conjugates (ADCs) . Its auristatin E warhead potently inhibits tubulin polymerization. This compound is widely used in oncology research for developing targeted therapies and has demonstrated antitumor efficacy in both in vitro and in vivo models.
CAS Number
2055896-77-8
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] ([N+] (CC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCCCN4C (=O) C=CC4=O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C3) (C) C) C (C) C) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C68H108N11O13
Molecular Weight
1287.65
Storage Conditions
-20°C
Notes
For research use only.

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MBS3842972-01MC-Val-Cit-PAB-Auristatin E
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