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Palbociclib-propargyl

CAT: 0013-GTR19225122Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19225122Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CP-10 is a potent CDK6-targeting PROTAC composed of a palbociclib-based warhead linked to a CRBN ligand. It demonstrates high degradation potency with a DC50 of 2.1 nM, making it a valuable chemical probe for studying CDK6 biology in cancer research and for evaluating targeted protein degradation strategies in vitro.
CAS Number
2366269-23-8
Field of Research
Pharmacology & Drug Discovery
Smiles
CC (=O) c1c (C) c2cnc (Nc3ccc (cn3) N3CCN (CC#C) CC3) nc2n (C2CCCC2) c1=O
Molecular Formula
C27H31N7O2
Molecular Weight
485.58
Storage Conditions
-20°C
Notes
For research use only.

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