Linuron (Standard)

Linuron (Standard)

• CAS Number: 330-55-2
• UNSPSC Description: Linuron (Standard) is the analytical standard of Linuron. This product is intended for research and analytical applications. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor[1][2][3][4].
• Target Antigen: Androgen Receptor
• Type: Reference Standards
• Related Pathways: Vitamin D Related/Nuclear Receptor
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/linuron-standard.html
• Smiles: O=C(NC1=CC=C(Cl)C(Cl)=C1)N(OC)C
• Molecular Weight: 249.09
• References & Citations: [1]Benjamin Horemans, et al. Functional Redundancy of Linuron Degradation in Microbial Communities in Agricultural Soil and Biopurification Systems. Appl Environ Microbiol. 2016 Apr 18;82(9):2843-2853.|[2]C Lambright, et al. Cellular and Molecular Mechanisms of Action of Linuron: An Antiandrogenic Herbicide That Produces Reproductive Malformations in Male Rats. Toxicol Sci. 2000 Aug;56(2):389-99.|[3]Hongwei Ding, et al. Reproductive Toxicity of Linuron Following Gestational Exposure in Rats and Underlying Mechanisms. Toxicol Lett. 2017 Jan 15;266:49-55.|[4]Elżbieta G Magnucka, et al. Various Effects of the Photosystem II--inhibiting Herbicides on 5-n-alkylresorcinol Accumulation in Rye Seedlings. Pestic Biochem Physiol. 2014 Nov;116:56-62.
• Shipping Conditions: Room temperature