Linuron (Standard)

• Description :

  Linuron (Standard) is the analytical standard of Linuron. This product is intended for research and analytical applications. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor[1][2][3][4].

• UNSPSC :

  12352005

• Target :

  Androgen Receptor; Reference Standards

• Type :

  Reference Standards

• Related Pathways :

  Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/linuron-standard.html

• Smiles :

  O=C(NC1=CC=C(Cl)C(Cl)=C1)N(OC)C

• Molecular Formula :

  C9H10Cl2N2O2

• Molecular Weight :

  249.09

• References & Citations :

  [1]Benjamin Horemans, et al. Functional Redundancy of Linuron Degradation in Microbial Communities in Agricultural Soil and Biopurification Systems. Appl Environ Microbiol. 2016 Apr 18;82 (9) :2843-2853.|[2]C Lambright, et al. Cellular and Molecular Mechanisms of Action of Linuron: An Antiandrogenic Herbicide That Produces Reproductive Malformations in Male Rats. Toxicol Sci. 2000 Aug;56 (2) :389-99.|[3]Hongwei Ding, et al. Reproductive Toxicity of Linuron Following Gestational Exposure in Rats and Underlying Mechanisms. Toxicol Lett. 2017 Jan 15;266:49-55.|[4]Elżbieta G Magnucka, et al. Various Effects of the Photosystem II--inhibiting Herbicides on 5-n-alkylresorcinol Accumulation in Rye Seedlings. Pestic Biochem Physiol. 2014 Nov;116:56-62.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [330-55-2]