Products for Research Use Only
RegisterLogin

SPDH

CAT: 0013-GTR19224961-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19224961-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SPDH is a cleavable linker used in the construction of antibody-drug conjugates (ADCs) for targeted cancer therapy and B-cell disorder research. Its application facilitates the development of therapeutics evaluated in both in vitro assays and in vivo preclinical models for oncology and immunology.
CAS Number
1824718-79-7
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Smiles
O=C (ON1C (=O) CCC1=O) CCCCCSSC2=NC=CC=C2
Molecular Formula
C15H18N2O4S2
Molecular Weight
354.44
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-Succinimidyl-6-(2-Pyridyldithio)capronate
CAS Number1824718-79-7
PubChem CID88596426
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 6-(pyridin-2-yldisulfanyl)hexanoate
Molecular FormulaC15H18N2O4S2
Molecular Weight354.4
XLogP1.7
Topological Polar Surface Area127
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count10
Heavy Atom Count23
Formal Charge0
Complexity418
SMILES
C1CC(=O)N(C1=O)OC(=O)CCCCCSSC2=CC=CC=N2
InChI
InChI=1S/C15H18N2O4S2/c18-13-8-9-14(19)17(13)21-15(20)7-2-1-5-11-22-23-12-6-3-4-10-16-12/h3-4,6,10H,1-2,5,7-9,11H2
InChIKey
GUNOUNRTBRPXOQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-Succinimidyl-6-(2-Pyridyldithio)capronate
CAS: 1824718-79-7
CID: 88596426
Formula: C15H18N2O4S2
MW: 354.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight354.4
XLogP31.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count10
Exact Mass354.07079941
Monoisotopic Mass354.07079941
Topological Polar Surface Area127 Ų
Heavy Atom Count23
Formal Charge0
Complexity418
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19102589-01Recombinant Protein spdB (spdB)
GTR19168126SPDP
GTR19161022-01SPDP
GTR19111134-01Recombinant Protein spdA (spdA)
GTR19224947-01SPDV
GTR19170298-01SPDB
GTR19163576-01SPDB
GTR19231766DSPE-SPDP
GTR19224964-01SPDB-DM4
GTR19189812SPDP-sulfo

Alternative Products

CatalogName
BA2548-5SPDH

Popular Products