Tranexamic acid-d2-1

CAT: 0804-HY-B0149S1-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0804-HY-B0149S1-01Size:500 µg
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Description
Tranexamic acid-d2-1 is the deuterium labeled Tranexamic acid[1]. Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM[2][3].
CAS Number
[2714435-89-7]
UNSPSC
12352211
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cancer
Purity
99.19
Solubility
10 mM in DMSO
Smiles
OC([C@@H]1CC[C@H](CC1)C([2H])([2H])N)=O
Molecular Formula
C8H13D2NO2
Molecular Weight
159.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Bhat A, et al. Tranexamic acid overdosage-induced generalized seizure in renal failure. Saudi J Kidney Dis Transpl. 2014 Jan-Feb;25 (1) :130-2.|[3]Couturier R, et al. Continuous or discontinuous tranexamic acid effectively inhibits fibrinolysis in children undergoing cardiac surgery with cardiopulmonary bypass. Blood Coagul Fibrinolysis. 2014 Jan 13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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