Bismuth subcitrate (potassium)

Bismuth subcitrate (potassium)

• CAS Number: 880149-29-1
• UNSPSC Description: Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis[1][2][3].
• Target Antigen: Antibiotic; Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/bismuth-subcitrate-potassium.html
• Solubility: H2O : 100 mg/mL (ultrasonic)
• Smiles: O=C(O[Bi](OC(CC(C(O[K])=O)(O[K])CC(O[K])=O)=O)OC1=O)C(C1)(O[K])CC(O[K])=O
• Molecular Weight: 780.65542
• References & Citations: [1]Van Caekenberghe DL, et al. In vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against Campylobacter pyloridis (C. pylori). Antimicrob Agents Chemother. 1987 Sep;31(9):1429-30.|[2]Malfertheiner P, et al. Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. Lancet. 2011 Mar 12;377(9769):905-13.|[3]Hussar DA. New drugs: retapamulin, bismuth subcitrate potassium, and rotigotine. J Am Pharm Assoc (2003). 2007 Jul-Aug;47(4):539-43.
• Shipping Conditions: Blue Ice
• Clinical Information: Launched