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SJF620 hydrochloride

CAT: 0013-GTR19221835-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221835-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SJF620 hydrochloride is a potent CRBN-recruiting PROTAC degrader of Bruton's tyrosine kinase (Btk), with a DC50 of 7.9 nM. It is a valuable chemical tool for studying Btk function and degradation in both cellular and in vivo models of B-cell malignancies and autoimmune diseases.
CAS Number
2821938-05-8
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
NC1=C2C (=NN (C2=NC=N1) C3CCN (CCOCCOCCOC=4C=C5C (=CC4) C (=O) N (C5) C6C (=O) NC (=O) CC6) CC3) C7=CC=C (OC8=CC=CC=C8) C=C7.Cl
Molecular Formula
C41H45ClN8O7
Molecular Weight
797.3
Storage Conditions
-20°C
Notes
For research use only.

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