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Ribostamycin

CAT: 0013-GTR19221418-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221418-01Size:5 mg
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Description
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic effective against Gram-positive and Gram-negative bacteria. It also acts as a protein disulfide isomerase (PDI) inhibitor, making it a useful research tool for studying bacterial infections and PDI-related cellular processes in both in vitro and in vivo models.
CAS Number
25546-65-0
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
NC[C@H]1O[C@H] (O[C@@H]2[C@@H] (N) C[C@@H] (N) [C@H] (O) [C@H]2O[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H]2O) [C@H] (N) [C@@H] (O) [C@@H]1O
Molecular Formula
C17H34N4O10
Molecular Weight
454.47
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Ribostamycin

Ribostamycin is an amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-alpha-D-glucosyl residue attached at position 1 and a beta-D-ribosyl residue attached at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus). It has a role as a metabolite, an antimicrobial agent and an antibacterial drug. It is an amino cyclitol glycoside and an aminoglycoside antibiotic. It is a conjugate base of a ribostamycin(4+).

CAS Number25546-65-0
PubChem CID33042
IUPAC Name(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
Molecular FormulaC17H34N4O10
Molecular Weight454.5
XLogP-6.3
Topological Polar Surface Area262
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count14
Rotatable Bond Count6
Heavy Atom Count31
Formal Charge0
Complexity593
SMILES
C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)O)N
InChI
InChI=1S/C17H34N4O10/c18-2-6-10(24)12(26)8(21)16(28-6)30-14-5(20)1-4(19)9(23)15(14)31-17-13(27)11(25)7(3-22)29-17/h4-17,22-27H,1-3,18-21H2/t4-,5+,6-,7-,8-,9+,10-,11-,12-,13-,14-,15-,16-,17+/m1/s1
InChIKey
NSKGQURZWSPSBC-VVPCINPTSA-N
Chemical Structure
2D Structure
2D structure of Ribostamycin
CAS: 25546-65-0
CID: 33042
Formula: C17H34N4O10
MW: 454.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight454.5
XLogP3-6.3
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count14
Rotatable Bond Count6
Exact Mass454.22749329
Monoisotopic Mass454.22749329
Topological Polar Surface Area262 Ų
Heavy Atom Count31
Formal Charge0
Complexity593
Isotope Atom Count0
Defined Atom Stereocenter Count14
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5816200Ribostamycin
B1825-50Ribostamycin Sulfate
RM-R231000-01Ribostamycin; Vistamycin
AR46329-01Ribostamycin sulphate
HY-B1228-01Ribostamycin (sulfate)
GA7826-1gRibostamycin sulfate salt

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