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Bcl-2-IN-5

CAT: 0013-GTR19221352-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221352-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bcl-2-IN-5 is a highly potent small molecule BCL-2 inhibitor, showing sub-nanomolar IC50 values against wild-type and mutant (D103Y, G101V) proteins. It also demonstrates potent anti-proliferative activity in Bcl-2-G101V mutant RS4;11 cell lines. This inhibitor is a valuable research tool for studying apoptosis and resistance mechanisms in hematological cancers.
CAS Number
2728752-20-1
Field of Research
Cell Biology
Smiles
COc1ccc (CN2CCN (C3CC4 (C3) CN (C4) c3ccc (C (=O) NS (=O) (=O) c4ccc (NC[C@H]5CC[C@] (C) (O) CC5) c (c4) N (=O) =O) c (Oc4cnc5[nH]cc (F) c5c4) c3) [C@@H] (C2) c2ccccc2C (C) C) cc1
Molecular Formula
C55H63FN8O8S
Molecular Weight
1015.2
Storage Conditions
-20°C
Notes
For research use only.

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