Products for Research Use Only

PP-C8

CAT: 0013-GTR19221306-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221306-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PP-C8 is a potent and selective PROTAC that degrades CDK12 and Cyclin K with DC50 values of approximately 410 nM. It demonstrates synergistic antiproliferative activity with PARP inhibitors in triple-negative breast cancer models, making it a valuable chemical probe for oncology research targeting transcription-associated kinases.
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Molecular Formula
C43H51FN12O7
Molecular Weight
866.94
Storage Conditions
-20°C
Notes
For research use only.