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SJ10542

CAT: 0013-GTR19221244Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221244Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SJ10542 is a cereblon-recruiting PROTAC that potently and selectively degrades JAK2 and JAK3, with DC50 values in the low nanomolar range. This molecule is a valuable chemical tool for investigating JAK-dependent signaling in hematological malignancies and inflammatory disease models, both in vitro and in vivo.
CAS Number
2789678-92-6
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (C#N) C1 (CN (S (CC) (=O) =O) C1) N2C=C (C=N2) C3=C4C (=NC (NC5=CC=C (C (NCCCN6CCN (CC6) C7=CC=C (C=C7) C8C (=O) NC (=O) CC8) =O) C=C5) =N3) NC=C4
Molecular Formula
C41H46N12O5S
Molecular Weight
818.95
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T74429SJ10542

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