Products for Research Use Only

SS47

CAT: 0013-GTR19221176-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221176-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SS47 is a PROTAC-based small molecule that induces proteasome-mediated degradation of the immunosuppressive kinase HPK1. This degradation has been shown in research to enhance the antitumor efficacy of BCMA CAR-T cells in vivo, supporting its use in cancer immunotherapy studies.
CAS Number
2636072-62-1
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1C=2C=CC=C (OCCOCCOCCOCCOCCC (=O) N3CCC (C4=NC=C (S4) C=5C=NC (N) =C (OCC=6C=CC=C (C#CC (O) (C) C) C6) C5) CC3) C2C (=O) N1C7C (=O) NC (=O) CC7
Molecular Formula
C49H56N6O12S
Molecular Weight
953.07
Storage Conditions
-20°C
Notes
For research use only.

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