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Sonrotoclax

CAT: 0013-GTR19221072-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221072-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sonrotoclax (BGB-11417) is a potent and selective Bcl-2 inhibitor active against both wild-type and the G101V mutant protein. This investigational small molecule demonstrates antitumor activity in preclinical models of hematological malignancies, supporting its research in leukemia and lymphoma, including in vitro cellular assays and in vivo xenograft studies.
CAS Number
2383086-06-2
Product Name Alternative
BGB 11417, Bcl-2
Field of Research
Cell Biology
Purity
97.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.71 mM) ; DMSO:80 mg/mL (89.88 mM)
Smiles
CC (C1=C (C=CC=C1) [C@H]2N (CCC2) C3CC4 (CCN (C5=CC (OC6=CN=C (NC=C7) C7=C6) =C (C=C5) C (NS (=O) (C8=CC ([N+] ([O-]) =O) =C (C=C8) NC[C@@H]9CC[C@@] (O) (CC9) C) =O) =O) CC4) C3) C
Molecular Formula
C49H59N7O7S
Molecular Weight
890.10
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

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BA3335-1Sonrotoclax
BUP18611-01Sonrotoclax TFA

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