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Dideoxy-amanitin

CAT: 0013-GTR19221052-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221052-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dideoxy-amanitin is a potent and selective allosteric inhibitor of RNA polymerase II, with an IC50 of 74.2 nM. This α-Amanitin derivative is a valuable chemical tool for studying transcription mechanisms and has applications in both in vitro biochemical assays and in vivo research models.
CAS Number
58255-46-2
Field of Research
Cell Biology, Molecular Biology
Smiles
[H][C@@]12C[C@@H] (O) CN1C (=O) [C@H] (CC (N) =O) NC (=O) [C@]1 ([H]) CSc3[nH]c4ccccc4c3C[C@] ([H]) (NC (=O) [C@@] ([H]) (NC2=O) [C@@H] (C) [C@@H] (O) CO) C (=O) NCC (=O) N[C@@] ([H]) ([C@@H] (C) CC) C (=O) NCC (=O) N1
Molecular Formula
C39H54N10O12S
Molecular Weight
886.97
Storage Conditions
-20°C
Notes
For research use only.

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