Products for Research Use Only
RegisterLogin

AK-2292

CAT: 0013-GTR19220965-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19220965-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AK-2292 is a potent and selective PROTAC degrader of STAT5A/B proteins, demonstrating a DC50 of 0.10 μM. It effectively induces STAT5 degradation both in vitro and in vivo, and has shown activity in preclinical models of acute and chronic myeloid leukemia, supporting its use in oncology research.
CAS Number
2984506-77-4
Field of Research
Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (#CCCCN (C (CCN (C (=O) [C@H]1N (C ([C@@H] (NC (=O) C2=CC=3C (S2) =CC=C (C (P (=O) (O) O) (F) F) C3) [C@@] (C) (C) C) =O) CCC1) C4=CC=C (C=C4) C5=NC=CS5) =O) C) C6=C7C (C (=O) N (C7) C8C (=O) NC (=O) CC8) =CC=C6
Molecular Formula
C52H54F2N7O10PS2
Molecular Weight
1070.13
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19212114-01AK-IN-1
GTR19210887-01AK-106
GTR19210124-01AK-42
GTR19241092-01AK-4
GTR19169685-01AK-7
GTR19162574-01AK-1
GTR19199569-01AK 275
GTR19195782-01AK-135
GTR17909826-01AK Antibody
GTR19169581-01AK-1

Alternative Products

CatalogName
MBS5816687AK-2292
551493PKD1 (aa2281-2292)
STJ72612Anti-PKD1 (aa2281-2292) antibody
554773-01AK
dAP-2405Goat anti-PKD1 (aa2281-2292) Antibody
BA4517-50AK-1
B4713-25AK-7
HY-119131AK 275
T203554-01AK-4
T200953-01AK-068

Popular Products