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TMX1

CAT: 0013-GTR19220582Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19220582Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TMX1 is a covalent molecular glue that selectively recruits the CUL4-DCAF16 E3 ligase to the BD2 domain of BRD4, inducing its targeted degradation. This tool compound is valuable for probing BRD4 biology and BET protein function in both cellular and in vivo models of oncology and transcriptional regulation.
CAS Number
3079093-92-5
Product Name Alternative
TMX-1
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.57% (May vary between batches)
Solubility
DMSO:≥ 80 mg/mL;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.92 mM)
Smiles
CC=1C2=C (N3C ([C@H] (CC (OC (C) (C) C) =O) N=C2C4=CC=C (/C=C/C=O) C=C4) =NN=C3C) SC1C
Molecular Formula
C26H28N4O3S
Molecular Weight
476.59
Storage Conditions
-20°C
Notes
For research use only.

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