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ARCC-4

CAT: 0013-GTR19226720-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19226720-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ARCC-4 is a potent VHL-recruiting PROTAC that induces low-nanomolar degradation of the androgen receptor (DC50 = 5 nM) . It outperforms enzalutamide and effectively targets clinically relevant AR mutants, making it a valuable tool for prostate cancer research in both cellular and in vivo models.
CAS Number
1973403-00-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) COCCCCOc2ccc (cc2) -c2ccc (cc2) N2C (=S) N (C (=O) C2 (C) C) c2ccc (C#N) c (c2) C (F) (F) F) C (C) (C) C) cc1
Molecular Formula
C53H56F3N7O7S2
Molecular Weight
1024.18
Storage Conditions
-20°C
Notes
For research use only.

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