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NCI 126224

CAT: 0013-GTR19219829-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219829-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NCI 126224 is a selective TLR4 antagonist that potently inhibits LPS-induced nitric oxide (IC50 = 0.31 μM), NF-κB activity, and pro-inflammatory cytokine production in macrophages and microglial cells. It also shows activity against TLR2/6-mediated NO production, making it a useful research tool for studying innate immunity and inflammation in vitro.
CAS Number
65974-52-9
Field of Research
Immunology & Inflammation
Purity
99.95% (May vary between batches)
Smiles
COC (/C (C (OC) =O) =C/C1=C (C=CC=C1) [N+] ([O-]) =O) =O
Molecular Formula
C12H11NO6
Molecular Weight
265.2
Storage Conditions
-20°C
Notes
For research use only.

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