Sultamicillin

• Description :

  Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H320

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/sultamicillin.html

• Purity :

  98.32

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(OCOC([C@H](N1C2=O)C(C)(S[C@@]1([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)[H])C)=O)[C@H](N45)C(C)(S([C@@]4(CC5=O)[H])(=O)=O)C

• Molecular Formula :

  C25H30N4O9S2

• Molecular Weight :

  594.66

• Precautions :

  H315, H319, H320

• References & Citations :

  [1]Friedel HA, et al. Sultamicillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1989 Apr;37 (4) :491-522.|[2]English AR, et al. Pharmacokinetics of sultamicillin in mice, rats, and dogs. Antimicrob Agents Chemother. 1984 May;25 (5) :599-602.|[3]Assfalg V, et al. Combined immunosuppressive and antibiotic therapy improves bacterial clearance and survival of polymicrobial septic peritonitis. Shock. 2010 Feb;33 (2) :155-61. |[4]Qin HL, et al. Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA) . Eur J Med Chem. 2020 May 15;194:112245.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β-lactam

• CAS Number :

  [76497-13-7]