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C 101248

CAT: 0013-GTR19219784-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219784-04Size:25 mg
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Description
C 101248 (KCNK13-IN-1) is a potent and selective inhibitor of the THIK-1 (KCNK13) potassium channel. It suppresses IL-1β release in vitro and is a useful research tool for investigating neuroinflammation mechanisms in models of neurodegenerative disease.
CAS Number
361368-24-3
Product Name Alternative
C101248, KCNK13-IN-1
Field of Research
Pharmacology & Drug Discovery
Purity
99.14% (May vary between batches)
Solubility
DMSO:8 mg/mL (27.37 mM)
Smiles
N=1C=CC (=CC1) CN2C (=NC3=CC=CC=C32) C4=NON=C4N
Molecular Formula
C15H12N6O
Molecular Weight
292.3
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Kcnk13-IN-1
CAS Number361368-24-3
PubChem CID723233
IUPAC Name4-[1-(pyridin-4-ylmethyl)benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
Molecular FormulaC15H12N6O
Molecular Weight292.30
XLogP1.1
Topological Polar Surface Area95.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count22
Formal Charge0
Complexity377
SMILES
C1=CC=C2C(=C1)N=C(N2CC3=CC=NC=C3)C4=NON=C4N
InChI
InChI=1S/C15H12N6O/c16-14-13(19-22-20-14)15-18-11-3-1-2-4-12(11)21(15)9-10-5-7-17-8-6-10/h1-8H,9H2,(H2,16,20)
InChIKey
LXADAVBNVFYEBW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Kcnk13-IN-1
CAS: 361368-24-3
CID: 723233
Formula: C15H12N6O
MW: 292.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight292.30
XLogP31.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass292.10725903
Monoisotopic Mass292.10725903
Topological Polar Surface Area95.7 Ų
Heavy Atom Count22
Formal Charge0
Complexity377
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
8007/10C 101248

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