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LMTK3-IN-1

CAT: 0013-GTR19219589-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219589-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LMTK3-IN-1 is a potent, ATP-competitive inhibitor of Lemur Tyrosine Kinase 3 (Kd=2.5 μM) that induces its degradation via the ubiquitin-proteasome pathway. It demonstrates pro-apoptotic and anticancer activity in breast cancer cell lines (10-20 μM) and has shown efficacy in preclinical in vivo models of breast cancer.
CAS Number
2764850-23-7
Product Name Alternative
LMTK3IN1, LMTK3-IN-1, HGFR, cMet, c-Met/HGFR, c-Met, cMet/HGFR
Field of Research
Signal Transduction
Purity
99.58% (May vary between batches)
Solubility
DMSO:9.17 mg/mL (25.74 mM)
Smiles
FC (F) (F) OC1=CC=CC (=C1) C2=CN=C3C=CC (=NN32) C=4C=CN=CC4
Molecular Formula
C18H11F3N4O
Molecular Weight
356.3
Storage Conditions
-20°C
Notes
For research use only.

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