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IDH2R140Q-IN-2

CAT: 0013-GTR19218963-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218963-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IDH2R140Q-IN-2 is a potent, orally bioavailable inhibitor of the IDH2 R140Q mutant, demonstrating an IC50 of 29 nM against the enzyme. It effectively reduces D2HG levels in TF-1 cells (IC50=10 nM) and in tumor tissue, supporting its application in research models of acute myeloid leukemia (AML) .
CAS Number
2749568-16-7
Product Name Alternative
IDH2
Field of Research
Metabolism Research
Purity
99.85% (May vary between batches)
Smiles
FC (F) (F) C=1C=CC=C (C1) NC=2N=C (N=C (N2) N3CCC (O) C3) NC4=CC=CC (=C4) C (F) (F) F
Molecular Formula
C21H18F6N6O
Molecular Weight
484.4
Storage Conditions
-20°C
Notes
For research use only.

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