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Aurora Kinases-IN-4

CAT: 0013-GTR19218884-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218884-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aurora Kinases-IN-4 (Compound 11c) is a potent, covalent ATP-competitive inhibitor of Aurora A kinase (IC50 = 1.7 nM) . It exhibits anti-proliferative activity in various cancer cell lines, including triple-negative breast cancer models, making it a valuable chemical probe for oncology research.
CAS Number
2877011-84-0
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
N (C=1C2=C (N=C (N1) C3=CC=C (NC (C=C) =O) C=C3) C=C (C=C2) N4CCN (C) CC4) C5=NNC (C) =C5
Molecular Formula
C26H28N8O
Molecular Weight
468.55
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
MBS5820415Aurora Kinases-IN-4
MBS5805169Aurora Kinases-IN-2
MBS5814866Aurora Kinases-IN-3
048717-01Aurora Kinases (Aurora A/B/C) discontinued
T204214-01Aurora A inhibitor 4
HY-149354Aurora kinase-IN-4
145687PF 03814735 (Aurora Kinases A and B, N-[2-[ (1S,4R) -6-[[4- (Cyclobutylamin o) -5- (trifluoromethyl) -2-pyrimidinyl]amino]-1,2,3, 4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]- acetamide)
217204Aurora Kinase Inhibitor VI, ZM447439 (4- (4- (N-Benzoylamino) anilino) -6- methoxy-7- (3- (1-morpholino) propoxy) quinazoline)
MBS6326906-01NSUN2, ID (NSUN2, SAKI, TRM4, tRNA (cytosine(34)-C(5))-methyltransferase, Myc-induced SUN domain-containing protein, NOL1/NOP2/Sun domain family member 2, Substrate of AIM1/Aurora kinase B, tRNA (cytosine-5-)-methyltransferase, tRNA methyltransferase 4 ho
039167NSUN2, ID (NSUN2, SAKI, TRM4, tRNA (cytosine (34) -C (5) ) -methyltransferase, Myc-induced SUN domain-containing protein, NOL1/NOP2/Sun domain family member 2, Substrate of AIM1/Aurora kinase B, tRNA (cytosine-5-) -methyltransferase, tRNA methyltransferase 4 homolog)

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