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SIKs-IN-1

CAT: 0013-GTR19218883-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218883-01Size:25 mg
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Description
SIKs-IN-1 (compound 8h) is a potent and selective salt-inducible kinase (SIK) inhibitor that modulates macrophage polarization. It demonstrates anti-inflammatory effects by elevating IL-10 and suppressing IL-12, validated in both cellular assays and a DSS-induced murine colitis model for inflammatory disease research.
CAS Number
2927557-06-8
Field of Research
Signal Transduction
Smiles
C (NC1=C (C) C=CC=C1F) (=O) C=2C (NC3CCC3) =NC (NC4=CC (F) =C (C=C4) N5CCN (C) CC5) =NC2
Molecular Formula
C27H31F2N7O
Molecular Weight
507.58
Storage Conditions
-20°C
Notes
For research use only.

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