Products for Research Use Only
RegisterLogin

THR-β modulator-1

CAT: 0013-GTR19218777-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19218777-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
THR-β Modulator-1 (Compound 1a) is a potent and selective thyroid hormone receptor beta (THR-β) agonist. It is a valuable research tool for studying metabolic disorders, including NASH and dyslipidemia, in both in vitro and in vivo experimental models.
CAS Number
2770373-00-5
Field of Research
Metabolism Research
Smiles
O (C=1C2=C ([C@H] (C) CC2) C (=O) NN1) C3=C (Cl) C=C (C=C3Cl) N4C (=O) NC (=O) C (N) =N4
Molecular Formula
C17H14Cl2N6O4
Molecular Weight
437.24
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

THR-|A modulator-1
CAS Number2770373-00-5
PubChem CID163293556
IUPAC Name6-amino-2-[3,5-dichloro-4-[[(7R)-7-methyl-1-oxo-2,5,6,7-tetrahydrocyclopenta[d]pyridazin-4-yl]oxy]phenyl]-1,2,4-triazine-3,5-dione
Molecular FormulaC17H14Cl2N6O4
Molecular Weight437.2
XLogP2
Topological Polar Surface Area138
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count29
Formal Charge0
Complexity860
SMILES
C[C@@H]1CCC2=C1C(=O)NN=C2OC3=C(C=C(C=C3Cl)N4C(=O)NC(=O)C(=N4)N)Cl
InChI
InChI=1S/C17H14Cl2N6O4/c1-6-2-3-8-11(6)14(26)22-23-16(8)29-12-9(18)4-7(5-10(12)19)25-17(28)21-15(27)13(20)24-25/h4-6H,2-3H2,1H3,(H2,20,24)(H,22,26)(H,21,27,28)/t6-/m1/s1
InChIKey
BWAVFVPASXWWGI-ZCFIWIBFSA-N
Chemical Structure
2D Structure
2D structure of THR-|A modulator-1
CAS: 2770373-00-5
CID: 163293556
Formula: C17H14Cl2N6O4
MW: 437.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight437.2
XLogP32
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass436.0453583
Monoisotopic Mass436.0453583
Topological Polar Surface Area138 Ų
Heavy Atom Count29
Formal Charge0
Complexity860
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19234573-01THR-β modulator-2
GTR19274274-01THR-β modulator-3
GTR19240312-01α-Synuclein modulator 1
GTR19239643-01Gpr35 modulator 1
GTR19235065-01KCC2 Modulator-1
GTR19234951-01MRGPRX2 modulator-1
GTR19233068-01Pin1 modulator 1
GTR19275001-01KLK7 modulator-1
GTR19274822-01KCNQ2 modulator-1
GTR19274671-01APP modulator-1

Alternative Products

CatalogName
T79089-01THR-β modulator-1
MBS5820750THR-beta modulator-1
HY-160416THR-β modulator-2
HY-142441-01THR-β agonist 1
HY-153535THRβ receptor agonist-1
sc-24628FKHRL-1 (Thr 32)
MBS5805252THR-beta agonist 1
E-2430.0025H-Thr-OBzl · oxalate (1:1)
4104329.2002(Thr²) -Amyloid β-Protein (1-42)
LLA95952-01Glcnacβ (1-3) GalNAc-α-Thr

Popular Products