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P2X3 antagonist 38

CAT: 0013-GTR19218766-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218766-01Size:25 mg
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Description
Compound 38 (Compound 4) is an orally bioavailable, potent P2X3 receptor antagonist, exhibiting IC50 values of 0.132 μM (hP2X3), 0.165 μM (rP2X3), and 0.421 μM (gpP2X3) . This small molecule is a valuable research tool for investigating P2X3-mediated pathways in pain and cough models, applicable in both in vitro and in vivo studies.
CAS Number
2545974-71-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
N (C (OCC) =O) (C) [C@@H]1C (=NN (C (N[C@H] (C) C=2C=NC (C (F) (F) F) =NC2) =O) C1) C3=CC=C (C) C=C3
Molecular Formula
C22H25F3N6O3
Molecular Weight
478.47
Storage Conditions
-20°C
Notes
For research use only.

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