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RDN2150

CAT: 0013-GTR19218685-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218685-02Size:5 mg
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Description
RDN2150 (Compound 25) is a potent and covalent ZAP-70 inhibitor (IC50=14.6 nM) targeting C346. It suppresses CD25/CD69 expression and CD4+ T cell activation, supporting its application in immunology and autoimmune disease research, such as psoriasis, in both in vitro and in vivo studies.
CAS Number
2839429-51-3
Field of Research
Protein Biochemistry
Smiles
O=C (C=C) NC1=CC (=CC=C1Cl) CNC2=NC (NC3=CC=C (C (OC) =C3) N4CCOCC4) =C (C (=O) N) C5=NC=CN25
Molecular Formula
C28H29ClN8O4
Molecular Weight
577.03
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-[[4-Chloro-3-(prop-2-enoylamino)phenyl]methylamino]-7-(3-methoxy-4-morpholin-4-ylanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
CAS Number2839429-51-3
PubChem CID168510605
IUPAC Name5-[[4-chloro-3-(prop-2-enoylamino)phenyl]methylamino]-7-(3-methoxy-4-morpholin-4-ylanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Molecular FormulaC28H29ClN8O4
Molecular Weight577.0
XLogP4.3
Topological Polar Surface Area148
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count10
Heavy Atom Count41
Formal Charge0
Complexity910
SMILES
COC1=C(C=CC(=C1)NC2=C(C3=NC=CN3C(=N2)NCC4=CC(=C(C=C4)Cl)NC(=O)C=C)C(=O)N)N5CCOCC5
InChI
InChI=1S/C28H29ClN8O4/c1-3-23(38)34-20-14-17(4-6-19(20)29)16-32-28-35-26(24(25(30)39)27-31-8-9-37(27)28)33-18-5-7-21(22(15-18)40-2)36-10-12-41-13-11-36/h3-9,14-15,33H,1,10-13,16H2,2H3,(H2,30,39)(H,32,35)(H,34,38)
InChIKey
PUDSDEKTPDXOGR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-[[4-Chloro-3-(prop-2-enoylamino)phenyl]methylamino]-7-(3-methoxy-4-morpholin-4-ylanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
CAS: 2839429-51-3
CID: 168510605
Formula: C28H29ClN8O4
MW: 577.0
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight577.0
XLogP34.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count10
Exact Mass576.2000291
Monoisotopic Mass576.2000291
Topological Polar Surface Area148 Ų
Heavy Atom Count41
Formal Charge0
Complexity910
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T81308-01RDN2150
HY-155978A-01RDN2150 (TFA)

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