Products for Research Use Only

Os30

CAT: 0013-GTR19219201-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219201-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Os30 is a potent fourth-generation EGFR inhibitor targeting the EGFR C797S mutation, with IC50 values of 18 nM and 113 nM for common triple-mutant variants. It inhibits phosphorylation, induces cell cycle arrest and apoptosis in vitro, and demonstrates antitumor activity in NSCLC models harboring EGFR C797S mutations.
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.