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(±) -Longamide

CAT: 0804-HY-W834359-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W834359-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) -Longamide is a polycyclic bioactive metabolite isolated from sponges that has several bromopyrrole fragments, as well as a weak inhibitor of IDO1[1].
CAS Number
219783-00-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite; Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/racemic-longamide.html
Smiles
O=C1NCC(N2C(Br)=C(C=C12)Br)O
Molecular Formula
C7H6Br2N2O2
Molecular Weight
309.94
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]S. Marchais, et al. Synthesis of the marine carbinolamine (+/−) longamide control of N-1 and C-3 bromopyrrole nucleophilicity. Tetrahedron Letters. Volume 40, Issue 30, 23 July 1999, Pages 5519-5522.|[2]Shiokawa Z, et al. Discovery of a Novel Scaffold as an Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Based on the Pyrrolopiperazinone Alkaloid, Longamide B. ChemMedChem. 2016 Dec 16;11 (24) :2682-2689.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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