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Senexin B

CAT: 0013-GTR19217394-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19217394-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Senexin B (SNX2-1-165) is a highly potent, selective and orally available CDK8/CDK19 inhibitor with IC50 of 24-50 nM; exhibits selectivity for CDK8 and CDK19 with Kd of 140 nM and 80 nM, respectively; significantly suppresses tumor growth in ER-positive breast cancer xenografts.
CAS Number
1449228-40-3
Product Name Alternative
SNX2-1-165
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (C1=CC2=CC=C (CCNC3=C4C (C=CC (C#N) =C4) =NC=N3) C=C2C=C1) N5CCN (C) CC5
Molecular Formula
C27H26N6O
Molecular Weight
450.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- ((2- (6- (4-Methylpiperazine-1-carbonyl) naphthalen-2-yl) ethyl) amino) quinazoline-6-carbonitrile

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