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LY-3177833

CAT: 0013-GTR19217389-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19217389-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective CDC7 inhibitor with IC50 of 3.3 nM. (In Vitro) :LY3177833 (10 μM; 4 days) increases SA-β-gal content in Hep3B cells. (In Vivo) :LY3177833 (Example 4; 10.4-31.2 mg/kg; oral gavage; twice a day; for 2 weeks; female athymic Balb/c nude mice with SW620 cells) treatment causes significant tumor regression in a dose-dependent manner. Also, no significant tumor growth is observed for 2 weeks after dosing cessation.
CAS Number
1627696-51-8
Product Name Alternative
LY3177833
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 30 mg/mL
Smiles
O=C1N[C@@] (C) (C2=NC=NC=C2F) C3=C1C=C (C4=CNN=C4) C=C3
Molecular Formula
C16H12FN5O
Molecular Weight
309.2978
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Isoindol-1-one, 3- (5-fluoro-4-pyrimidinyl) -2,3-dihydro-3-methyl-6- (1H-pyrazol-4-yl) -, (3R) -

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Alternative Products

CatalogName
MBS5758677LY-3177833
A16325-100LY-3177833 100mg
A16325-1LY-3177833 1mg
A16325-200LY-3177833 200mg
A16325-50LY-3177833 50mg
A16325-5LY-3177833 5mg
A16325-25LY-3177833 25mg
A16325-10LY-3177833 10mg
A16325-10mM-DLY-3177833 10mM * 1mL in DMSO
228143CD5 (Ly-1, Ly-12, Ly-A, T1, Tp67)

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