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Cycloheximide

CAT: 0013-GTR19217342-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19217342-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cycloheximide (Naramycin A, Actidione) is a widely-used protein synthesis inhibitor that inhibits protein biosynthesis in eukaryotic organisms with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively; block the elongation phase of eukaryotic translation, binds the ribosome and inhibits eEF2-mediated translocation; impairs memory more as footshock intensity increases, enhances memory in an inverted-U dose-response manner at low dose; also sensitizes COLO 205 cells to TNF-alpha-induced programmed cell death.
CAS Number
66-81-9
Product Name Alternative
Naramycin A | Actidione
Purity
>98% (HPLC)
Solubility
DMSO: >33 mg/mL; H2O: 20 mg/mL (Need ultrasonic and warming)
Smiles
O=C (CC (C[C@H] ([C@H]1C ([C@@H] (C) C[C@H] (C) C1) =O) O) C2) NC2=O
Molecular Formula
C15H23NO4
Molecular Weight
281.3474
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2,6-Piperidinedione, 4-[ (2R) -2-[ (1S,3S,5S) -3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-

Alternative Products

CatalogName
C12670-500mgCycloheximide

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