Products for Research Use Only
RegisterLogin

Cefotaxime

CAT: 0013-GTR19217280-02Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19217280-02Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cefotaxime is an inhibitor of penicillin binding protein. (In Vitro) :Cefotaxime exhibits an MIC of 0.0625 mg/L for V. vulnificus CMCP6. (In Vivo) :The combination of ciprofloxacin and cefotaxime is more effective in clearing V. vulnificus in vivo than previously used regimens.
CAS Number
63527-52-6
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:91 mg/mL (199.79 mM)
Smiles
CO/N=C (\C (=O) N[C@@H]1C (=O) N2C (C (=O) O) =C (COC (C) =O) CS[C@H]12) c1csc (N) n1
Molecular Formula
C16H17N5O7S2
Molecular Weight
455.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(6R7R) -3- (acetoxymethyl) -7- ((Z) -2- (2-aminothiazol-4-yl) -2- (methoxyimino) acetamido) -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Chemical Information

Cefotaxime

Cefotaxime is a cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups. It has a role as an antibacterial drug and a drug allergen. It is a cephalosporin, an oxime O-ether and a member of 1,3-thiazoles. It is a conjugate acid of a cefotaxime(1-).

CAS Number63527-52-6
PubChem CID5742673
IUPAC Name(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular FormulaC16H17N5O7S2
Molecular Weight455.5
XLogP-1.4
Topological Polar Surface Area227
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count8
Heavy Atom Count30
Formal Charge0
Complexity833
SMILES
CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)O
InChI
InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1
InChIKey
GPRBEKHLDVQUJE-QSWIMTSFSA-N
Chemical Structure
2D Structure
2D structure of Cefotaxime
CAS: 63527-52-6
CID: 5742673
Formula: C16H17N5O7S2
MW: 455.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight455.5
XLogP3-1.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count8
Exact Mass455.05694025
Monoisotopic Mass455.05694025
Topological Polar Surface Area227 Ų
Heavy Atom Count30
Formal Charge0
Complexity833
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA1012-500Cefotaxime
RM-C202456-01Cefotaxime Impurity 30 (Cefotaxime S-Oxide)
AR-C01916-01Cefotaxime EP Impurity F (Cefotaxime Dimer)
C39SD1043Cefotaxime (Cephotaxime)

Popular Products