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Thiazolyl Blue

CAT: 0013-GTR19217271Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19217271Size:1 g
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Description
Thiazolyl Blue (MTT) is used in conjunction with rhodamine B to measure mitochondrial membrane potential. Thiazolyl Blue-formazan is generated in mitochondria acts as a fluorescence quencher for rhodamine that distributes across membranes of viable cells according to membrane potential. In the absence of mPMS, cellular reduction of Thiazolyl Blue is strong. Thiazolyl Blue is membrane-impermeable when incorporated into large unilamellar liposomes, and therefore it is taken up by cells via endocytosis.
CAS Number
298-93-1
Purity
>98% (HPLC)
Solubility
DMSO : 25 mg/mL (60.34 mM; Need ultrasonic) ; H2O : 0.88 mg/mL (2.12 mM; Need ultrasonic and warming)
Smiles
CC1=C (C) N=C (N2N=C (C3=CC=CC=C3) N=[N+]2C4=CC=CC=C4) S1.[Br-]
Molecular Formula
C??H??BrN?S
Molecular Weight
414.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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