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Pyridoxylamine

CAT: 0013-GTR19216914-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216914-01Size:200 mg
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Description
Pyridoxylamine is an inhibitor of advanced glycation end production (AGEs) and lipoxidation end products (ALEs) . (In Vitro) :Pyridoxylamine (PM) is a member of the B6 vitamer family, and is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation. (In Vivo) :In STZ diabetic rats, Pyridoxylamine inhibited the formation of CML and CEL and the cross-linking of skin collagen, ultimately inhibiting the development of nephropathy. Pyridoxamine does not appear to act as an antioxidant because it does not inhibit lipid peroxidation. However, it prevents modification of proteins by lipid peroxidation products, including inhibition of the formation of adducts of malondialdehyde and 4-hydroxynonenal on proteins in Zucker rats .
CAS Number
85-87-0
Product Name Alternative
Pyridoxamine
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 16.67 mg/mL (99.11 mM)
Smiles
OCC1=C (CN) C (O) =C (C) N=C1
Molecular Formula
C8H12N2O2
Molecular Weight
168.19
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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