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Thiamine nitrate

CAT: 0013-GTR19216885-01Size: 1 gDry Ice: NoHazardous: No
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Description
Thiamine nitrate is an essential vitamin, and can enhance normal neuronal actives. (In Vitro) :In the blood of homozygous KO and KI mice , Thiamine levels fed a conventional diet are decreased to 0.058±0.051 and 0.126±0.092 μM, respectively, at 7 weeks compare to WT mice (0.796±0.259 μM) . When WT and homozygous KO and KI mice are fed a Thiamine-restricted diet (Thiamine: 0.60 mg/100 g food), blood Thiamine concentration at 5 and 14 days is markedly decreased to 0.010±0.009 and 0.010±0.006 μM, respectively, compare to WT mice (0.609±0.288 μM) . Thiamine concentration in brain homogenate of WT mice fed a conventional diet is 3.81±2.18 nmol/g wet weight, and that of KO and KI is 1.33±0.96 and 2.16±1.55 nmol/g wet weight, respectively. Notably, Thiamine concentration in brain homogenate decreases steadily in KO and KI mice fed a thiamine-restrict diet (Thiamine: 0.60 mg/100 g food) for 5 days (0.95±0.72 nmol/g wet weight) and 14 days (1.11±0.24 nmol/g wet weight), respectively, compare to WT (3.65±1.02 nmol/g wet weight), before the mice presenting an phenotype of disease.
CAS Number
532-43-4
Product Name Alternative
Vitamin B1 nitrate
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 20 mg/mL (61.09 mM)
Smiles
[O-][N+] ([O-]) =O.Cc1c (CCO) sc[n+]1Cc1cnc (C) nc1N
Molecular Formula
C12H17N5O4S
Molecular Weight
327.36
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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