Products for Research Use Only

JNJ-61432059

CAT: 0013-GTR19216854-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19216854-01Size:1 g
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Description
JNJ-61432059 is an oral active and selective negative modulator of TARP γ 8 Selective AMPAR (pIC50: 9.7) . (In Vivo) :In mouse hippocampus, Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models.
CAS Number
2035814-50-5
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (112.75 mM)
Smiles
OC1CCN (CC1) c1nccc2c (c (nn12) -c1ccc (F) cc1) -c1ccc2NC (=O) Cc2c1
Molecular Formula
C25H22FN5O2
Molecular Weight
443.482
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.