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Pivanex

CAT: 0013-GTR19216838-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19216838-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pivanex is an orally active HDAC inhibitor and an antimetastatic and antiangiogenic agent. Pivanex downregulates the Bcr-Abl protein and enhances apoptosis. (In Vitro) :In K562 cells, Pivanex (100-500 μM) exhibits significant anti-proliferation activity and enhances apoptosis and caspase activity. Pivanex (200 μM) induces enhancement in the G2-M phase, a moderate enhancement in the S phase, and a slight reduction in G0-G1 of the cell cycle. (In Vivo) :Pivanex (200 mg/kg, b.i.d, daily) treatment marked delays in the end stage of disease as defined by the onset of body mass loss by 94.9%. Pivanex (200 mg/kg, b.i.d, daily) obviously improves the survival of SMN7 SMA mice by 84.6%.
CAS Number
122110-53-6
Product Name Alternative
AN-9 | Pivalyloxymethyl butyrate
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : ≥ 100 mg/mL (494.44 mM)
Smiles
CCCC (=O) OCOC (=O) C (C) (C) C
Molecular Formula
C10H18O4
Molecular Weight
202.25
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
BA3064-50Pivanex
A24045-50Pivanex (AN-9) 50mg
A24045-25Pivanex (AN-9) 25mg
A24045-500Pivanex (AN-9) 500mg
A24045-100Pivanex (AN-9) 100mg

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