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M-PEG12-OH

CAT: 0013-GTR19216782-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216782-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . (In Vitro) :PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
CAS Number
2050595-03-2
Product Name Alternative
Dodecaethylene Glycol Monomethyl Ether
Purity
>98% (HPLC)
Smiles
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Molecular Formula
C25H52O13
Molecular Weight
560.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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