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DMPO

CAT: 0013-GTR19216891-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19216891-01Size:1 g
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Description
DMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance. It has a high reaction rate constant for superoxide and hydroxyl radicals and distinguishes simultaneously among a variety of important biologically generated free radicals. (In Vitro) :It was demonstrated in red blood cells and in hamster V79 cells that the DMPO spin adducts of ·O2 and ·OH are metabolized very rapidly so that even if formed, they may not be detected in many experiments with cells . (In Vivo) :When DMPO perfused the heart at 100 μm/L, it attenuated the development of reperfusion arrhythmias during the first 10 min of reperfusion and improved the functional recovery of the heart during reperfusion. Without treatment, 55% of hearts showed irreversible ventricular fibrillation, and this was completely prevented by DMPO, due to its function of traping·O2 and ·OH radicals .
CAS Number
3317-61-1
Product Name Alternative
5,5-Dimethyl-1-pyrroline N-oxide
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : ≥ 100 mg/mL (883.70 mM) )
Smiles
CC1 (C) CCC=[N+]1[O-]
Molecular Formula
C6H11NO
Molecular Weight
113.16
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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