Products for Research Use Only
RegisterLogin

Zapnometinib

CAT: 0013-GTR19216440-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19216440-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Zapnometinib is a MEK inhibitor. (In Vitro) :Zapnometinib inhibits MEK, with IC50s of 30.96 nM, 357 nM, and 15 nM in cell free kinase assay, A549, MDCK cells and human PBMCs.Zapnometinib reduces the viral titers of the IV H1N1pdm09, H3N2. (In Vivo) :Zapnometinib exhibits AUC values of 860.02 and 1953.68 μg h/mL in mice by i.v. or oral route, respectively.Zapnometinib reduces the lung virus titers and enhances survival of mice after lethal H1N1pdm09 infection.
CAS Number
303175-44-2
Product Name Alternative
2- (2-chloro-4-iodoanilino) -3,4-difluorobenzoic acid | PD0184264 | ATR-002
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 62.5 mg/mL (152.61 mM)
Smiles
OC (c (c (Nc (ccc (I) c1) c1Cl) c1F) ccc1F) =O
Molecular Formula
C13H7ClF2INO2
Molecular Weight
409.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
T9321-01Zapnometinib
E0404-01Zapnometinib (PD0184264)

Popular Products