Products for Research Use Only
RegisterLogin

GNE-0749

CAT: 0013-GTR19213365Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19213365Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GNE-0749 is a potent and selective pan-RAF inhibitor with Ki of 0.061 nM and <0.08 nM for CRAF and BRAF, respectively. Combinated with cobimetinib, GNE-0749 demonstrates synergistic pharmacodynamic effects in the KRAS mutant HCT116 tumor-bearing mice.
Purity
>98%
Smiles
N (CCC (C) (C) C) C (NC1=CC (NC2C=CC3=C (C=2F) C (=O) N (C) C=N3) =C (C) C=C1F) =O
Molecular Formula
C23H27F2N5O2
Molecular Weight
443.5
Notes
For research use only.

Related Products

CatalogName
GTR19224371-01GNE-886
GTR19205747-01GNE-616
GTR19205745-01GNE-8505
GTR19198468-01GNE-140
GTR19194441-01GNE-3476
GTR19189192GNE-274
GTR19203302GNE-0946
GTR19333488GNE-371
GTR19172785-01GNE-490
GTR19170974-01GNE-477

Alternative Products

CatalogName
317648GNE
BA8317-5GNE-6468
B4991-50GNE-317
BA4704-10GNE-375
BA3885-5GNE-6776
B1271-100GNE-617
BA8045-50GNE-618
B8001-5GNE-477
BA6483-10GNE-1858
BA8320-5GNE-0946

Popular Products