Products for Research Use Only

Efflux inhibitor-1

CAT: 0013-GTR19212730-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212730-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Efflux inhibitor-1 is a pyrazolopyrimidine-based compound that selectively inhibits the ABCG2/BCRP transporter over ABCB1, with respective IC50 values of 0.45 μM and 2.17 μM. It is a valuable research tool for studying multidrug resistance and pharmacokinetics in both cellular and animal models.
CAS Number
1776055-29-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O (C) C1=C (C2=NN3C (=CC (=NC3=C2) C4=CC=CC=C4) N5CCN (C (=O) C=6C=COC6) CC5) C=CC=C1
Molecular Formula
C28H25N5O3
Molecular Weight
479.53
Storage Conditions
-20°C
Notes
For research use only.