Products for Research Use Only

NCGC00138783

CAT: 0013-GTR19212527-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212527-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NCGC00138783 is a selective small molecule inhibitor that disrupts the CD47-SIRPα interaction with an IC50 of 50 μM. This blockade can enhance macrophage-mediated phagocytosis in vitro and is used in immuno-oncology research to investigate therapeutic strategies targeting the "don't eat me" signal.
Smiles
CCC (C (=O) NC1=CC=C (C=C1) F) SC2=NC3=CC=CC=C3C4=NC (=NN42) CCC5=C (NN=C5C) C.C (=O) (C (F) (F) F) O.C (=O) (C (F) (F) F) O
Molecular Formula
C30H28F7N7O5S
Molecular Weight
731.64
Storage Conditions
-20°C
Notes
For research use only.