Products for Research Use Only

NLRP3-IN-12

CAT: 0013-GTR19212447-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212447-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3-IN-12 is a potent and selective NLRP3 inflammasome inhibitor with an IC50 of 0.45 μM, directly targeting the NLRP3 protein to block IL-1β release. It is a valuable research tool for studying inflammatory diseases, including inflammatory bowel disease, in both cellular and animal models.
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
CC1 (CC[C@@H] ([C@]23[C@@H]1[C@@H] ([C@] ([C@]45[C@H]2CC[C@H] (C4OC (=O) NC6=CC (=CC=C6) Cl) C (=C) C5=O) (OC3) O) O) O) C
Molecular Formula
C27H32ClNO7
Molecular Weight
518
Storage Conditions
-20°C
Notes
For research use only.