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ATR-IN-20

CAT: 0013-GTR19212233-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212233-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATR-IN-20 is a highly potent dual inhibitor of ATM/ATR (IC50=3 nM) and mTOR (IC50=18 nM) with significant selectivity over related kinases. It demonstrates favorable oral bioavailability (F=30%) and exhibits promising anticancer activity in both cellular and animal models, supporting its use in DNA damage response and oncology research.
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
C[C@@H]1COCCN1C2=NC (=NC3=C2CN (C3 (C) C) C (=O) C4=CC (=CC=C4) S (=O) (=O) C) C5=C6C=CNC6=CC=C5
Molecular Formula
C29H31N5O4S
Molecular Weight
545.65
Storage Conditions
-20°C
Notes
For research use only.

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