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PV-1019

CAT: 0013-GTR19212134-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212134-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PV-1019 (NSC 744039) is a potent and selective Chk2 inhibitor with an IC50 of 24 nM. It blocks Topotecan-induced Chk2 autophosphorylation and IR-induced apoptosis, making it a valuable chemical probe for studying DNA damage response pathways in both cellular and animal models of cancer research.
CAS Number
1093793-05-5
Field of Research
Cell Biology
Smiles
N (=O) (=O) C1=C2C (C=C (C (NC3=CC=C (C (=NNC (=N) N) C) C=C3) =O) N2) =CC=C1
Molecular Formula
C18H17N7O3
Molecular Weight
379.37
Storage Conditions
-20°C
Notes
For research use only.

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