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Litoxetine

CAT: 0013-GTR19211729-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19211729-01Size:1 mg
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Description
Litoxetine is a dual-acting small molecule that selectively inhibits serotonin (5-HT) reuptake and antagonizes the 5-HT3 receptor. It exhibits antidepressant and antiemetic activities, as demonstrated by its dose-dependent reduction of vomiting in ferret models and its affinity for central 5-HT3 receptors (Ki = 85 nM) . This profile supports its research use in neuropharmacology and emesis studies.
CAS Number
86811-09-8
Product Name Alternative
5-HT transporter, 5-HT3, 5HT Receptor, 5HTReceptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.12% (May vary between batches)
Solubility
DMSO:10 mg/mL (41.44 mM)
Smiles
C (OC1CCNCC1) C2=CC3=C (C=C2) C=CC=C3
Molecular Formula
C16H19NO
Molecular Weight
241.33
Storage Conditions
-20°C
Notes
For research use only.

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BUP12423-01Litoxetine
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MBS5810530Litoxetine HCl
AR-L07572-01Litoxetine-d5 HCl
AR-L07577-01N-Nitroso Litoxetine
AR-L07573-01Litoxetine-d9 HCl

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